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Diagnostic Testing & Technology Report

September 2008

Gene Variations Affect Response to Antidepressant Celexa

A study published early online by the American Journal of Medical Genetics Part B: Neuropsychiatric Genetics shows that variations in the serotonin transporter gene could explain why some people with depression respond better than others to treatment with Celexa (citalopram), an antidepressant. The Mayo Clinic study of 1,914 subjects shows that two variations in the serotonin transporter gene (SLC6A4) have a direct bearing on how individuals might respond to citalopram.

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September 2008 - Table of Contents


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